Characters that have been turned into Toads cannot cast spells and their attacks will always miss. Any item they use will have minimal effect, meaning they cannot use a Maiden's Kiss during battle to remove Toad. Being a Toad counts as being out of combat, so if every party member is a Toad (or KO'd, Stone, etc.), the game is over. Monsters afflicted with Toad leave the battlefield immediately as if killed.